Women may get help to grow new eggs from Cancer Drug.New research has found that treatment with common chemotherapy with drug combination appears to increase the number of new eggs in the ovaries of women.
But it is too early to say anything for sure. We can’t link it with fertility yet. Researchers believe that more research needed to understand the finding and implication of the findings which publish in the journal Human Reproduction. Until now it was thought to be impossible to find how women are able to create eggs in their whole lifetime. But if this research can reveal the mechanism by which treatment with the drug combination, known as ABVD, results in increased production of eggs, that impossible might become possible. May be we will finally be able to unveil that mystery.
Lead researcher Evelyn Telfer, Professor at University of Edinburgh in Britain said “This study involves only a few patients, but its findings were consistent and its outcome may be significant and far-reaching. We need to know more about how this drug combination acts on the ovaries, and the implications of this.”
For the research 14 women who had undergone chemotherapy and 12 healthy women gave the sample of ovary tissue which was analyzed by the researcher. The research showed that the ovaries from eight of the cancer patients, who had been treated with a drug combination, had a much greater incidence of immature, or non-growing, eggs compared with tissue from women who had received a different chemotherapy, or from healthy women of a similar age. The ovary tissue was seen to be in healthy condition, appearing similar to tissue from young women’s ovaries. Researchers had set out to understand better why treatment with ABVD is one of the few cancer drug combinations that do not impact women’s fertility.
Now future studies will examine the separate impact of each of the four drugs that combine to make ABVD — known as adriamycin, bleomycin, vinblastine and dacarbazine — to better understand the biological mechanisms involved.